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Market Crux Initiates Coverage On Citius Pharmaceuticals, Inc. (Nasdaq: CTXR) Starting This Morning—Monday, July 14, 2025
Here's Why…
Tight Float: There's fewer than 10M shares available—which could set the stage for big swing potential if demand begins to shift.
Analyst Targets: $4 and $6 price targets suggest up to 280% upside from recent levels.
Recent Momentum: An approx. 280% move from $0.65 to $2.48 between May 8 and July 3 has us buzzing about this one.
Launch Ready: LYMPHIR™ approved by FDA; full commercial rollout in motion.
3 Late-Stage Assets: Oncology, infection, GI—pipeline spans key unmet needs.
Strong Phase 3 Data: Mino-Lok® outperformed in catheter-related infection trial.
Cardinal Health Deal: National distribution locked in for LYMPHIR launch.
Take a look at (CTXR) this morning—the bell just rang…
July 14, 2025 At the Open: (CTXR) Lights Up Our Radar Right Now—Take An Early Look. Dear Reader, Take a look at (CTXR) while it's still early—the bell just rang. While much of the biotech space remains stuck in neutral, one under-the-radar name is quietly gaining speed—executing across multiple fronts with momentum that's tough to ignore. It's gearing up to launch a newly approved therapy, just delivered standout data in a high-risk infection category, and is advancing a third asset toward pivotal development—all while staying under most radars. With a maturing pipeline, late-stage programs, and a strategy grounded in real-world medical needs, Citius Pharmaceuticals, Inc. (Nasdaq: CTXR) may be approaching a pivotal moment in 2025. The company's multi-pronged approach has led to key regulatory achievements, near-term launch plans, and a pipeline designed to address persistent gaps in oncology, infectious disease, and gastrointestinal care. But here's what really stands out: (CTXR) has a tightly held float, with Yahoo reporting fewer than 10M shares listed as available to the public. That kind of limited supply could trigger sharp moves as demand shifts—and we've already seen signs of that playing out. From May 8 to July 3, (CTXR) moved approximately 280%—from $0.65 to $2.48. 
And the sentiment isn't just building on the charts—analyst coverage is starting to reflect growing attention. According to reports from Benzinga, GuruFocus, and TipRanks, D. Boral Capital analyst Jason Kolbert recently set a $6 target on (CTXR), which implies more than 280% upside potential from recent levels. Separately, Vernon Bernardino of H.C. Wainwright issued a $4 target, reflecting over 150% upside potential. As of Friday, (CTXR) was trending near or above its 5-day, 20-day, 50-day, and 100-day moving averages. With its 200-day average still ahead at 3.6266—and technical strength continuing to build—we've got all eyes on (CTXR) this morning. At the core of its evolution is a combination of disciplined capital allocation, pipeline maturity, and high-conviction science across three high-need categories: Cutaneous T-cell Lymphoma (CTCL), catheter-related bloodstream infections, and hemorrhoidal disease. LYMPHIR™: A Launch-Ready Oncology Asset
(CTXR)'s most advanced program, LYMPHIR™ (denileukin diftitox-cxdl), was FDA approved in August 2024 for adult patients with relapsed or refractory Stage I–III cutaneous T-cell lymphoma (CTCL) following at least one systemic therapy. This marks the first new systemic CTCL treatment approved since 2018, addressing a patient population with no curative therapies and limited options. (CTXR) has put approximately $90M into LYMPHIR, and full commercial launch is planned for 1H 2025 under the newly formed, Nasdaq-listed Citius Oncology, Inc. (Nasdaq: CTOR)—a majority-owned (92%) subsidiary. With a U.S. addressable market estimated at over $400M, LYMPHIR holds 12 years of BLA exclusivity and benefits from a concentrated prescriber base, allowing for commercial efficiency. Immuno-Oncology Expansion Potential
Beyond CTCL, (CTXR) is actively supporting investigator-initiated trials evaluating LYMPHIR in immuno-oncology settings. These include: - A Phase 1 trial with the University of Pittsburgh combining LYMPHIR with KEYTRUDA® for patients with recurrent or metastatic solid tumors, showing a 27% objective response rate, a 33% clinical benefit rate, and a median progression-free survival of 57 weeks in heavily pretreated patients.
- A Phase 1 trial at the University of Minnesota, exploring LYMPHIR as a preconditioning agent for CAR T-cell therapy in relapsed/refractory B-cell lymphomas.
These studies may lay the groundwork for broader label expansion beyond CTCL, with preliminary data from the solid tumor study already published and additional updates expected in 2025. Mino-Lok®: A Phase 3-Validated Infectious Disease Program
(CTXR) also completed a Phase 3 trial for Mino-Lok®, a novel antibiotic lock solution designed to salvage infected central venous catheters (CVCs). No current therapies are approved for catheter-related bloodstream infections (CRBSI or CLABSI), which affect approximately 500K U.S. patients annually and are associated with significant clinical and financial burdens. In a major late-stage study with 241 patients, Mino-Lok delivered standout results: - Patients treated with this therapeutic kept their catheters in place significantly longer—well past six weeks—compared to just 33 days in the control group.
- Overall treatment success was noticeably higher than the standard approach.
- And there were no serious safety issues tied to the therapeutic, with a risk profile similar to existing options.
The product is instilled into the catheter, never entering the bloodstream, offering a non-invasive, low-cost alternative to catheter removal and replacement—procedures that can cost up to $65K per infection episode. With Fast Track designation, Qualified Infectious Disease Product (QIDP) status, and market exclusivity extensions, Mino-Lok is positioned for regulatory advancement and commercial viability. The global CRBSI/CLABSI market is projected to exceed $2B. Halo-Lido: Advancing Toward Pivotal Development
Citius' third advanced program is Halo-Lido, a prescription cream for hemorrhoidal disease combining halobetasol propionate (a potent corticosteroid) and lidocaine hydrochloride. The Phase 2b trial has been completed, showing a meaningful reduction in symptom severity and validating a proprietary patient-reported outcome (PRO) instrument for use in pivotal trials. Hemorrhoidal disease affects over 10M people in the U.S., and Halo-Lido may become the first FDA-approved prescription product for this condition. Discussions with the FDA regarding Phase 3 development are underway. Strategic Strength and Execution
Citius has demonstrated a disciplined fin-anc-ial strategy, allocating resources to programs with clear clinical demand, significant market potential, and de-risked paths to commercialization. Management and shareholders are aligned, with $26.5M personally invested by founders, and a history of pharmaceutical execution across both development and go-to-market initiatives. The company has also protected its pipeline with a robust intellectual property portfolio, regulatory designations (Fast Track, QIDP), and long-term exclusivity rights extending through at least 2036 across key assets. Recent Developments
Citius Oncology Enters Distribution Agreement with Cardinal Health Ahead of LYMPHIR™ Launch
Citius Oncology, a subsidiary of Citius Pharmaceuticals (Nasdaq: CTXR), has signed a distribution agreement with Cardinal Health to support the U.S. launch of LYMPHIR™—an FDA-cleared therapeutic for relapsed or treatment-resistant cutaneous T-cell lymphoma (CTCL). Cardinal Health will handle national distribution, helping ensure reliable access to LYMPHIR for healthcare providers and eligible patients. Citius leadership calls the deal a major step in launch readiness, paving the way for broader availability across the U.S. LYMPHIR, approved in August 2024, targets IL-2 receptors on cancerous T-cells and has shown the ability to reduce harmful immune cells in CTCL. (CTXR) gained global rights (excluding parts of Asia) in 2021 and is now accelerating plans to bring this therapeutic to a patient group with limited treatment options and no known cure. 7 Reasons Why (CTXR) is Topping Our Watchlist This Morning
—Monday, July 14, 2025…
1. Small Float: With fewer than 10M shares listed as available to the public as reported by Yahoo, (CTXR) sits in a rare category where the potential for sharp moves may follow shifts in demand. 2. Analyst Coverage: Multiple analyst platforms—including TipRanks and Benzinga—have noted recent coverage with price targets of $4 and $6, suggesting potential upside of approximately 150% to 280% from recent levels for (CTXR). 3. Recent Momentum: Between May 8 and July 3, (CTXR) moved approximately 280%, from $0.65 to $2.48 in under two months. 4. Launch Readiness: (CTXR) is preparing for full commercial rollout of LYMPHIR™, an FDA-approved immunotherapy with 12 years of exclusivity in a hard-to-treat cancer category. 5. Pipeline Breadth: With three late-stage assets spanning oncology, infectious disease, and gastrointestinal care, (CTXR) has built a multi-category foundation with real clinical utility. 6. Phase 3 Data: (CTXR)'s Mino-Lok® demonstrated statistically superior outcomes in a pivotal study for catheter-related bloodstream infections, a space with no currently approved therapies. 7. Infrastructure Execution: With its distribution deal signed with Cardinal Health, (CTXR) now has logistics support in place to move LYMPHIR into the hands of providers nationwide. Pull Up (CTXR) While It's Still Early—The Bell Just Rang…
This one just landed on our radar—and the timing couldn't be more interesting. With momentum building, late-stage programs advancing, and launch infrastructure already snapping into place, Citius Pharmaceuticals, Inc. (Nasdaq: CTXR) is moving with purpose while much of the sector is still standing still. Between a very small float, recent momentum, analyst targets pointing significantly higher, and execution now accelerating behind an FDA-cleared asset—this setup checks more than a few boxes. We have all eyes on (CTXR) this morning. Pull up (CTXR) while it's still early—the bell just rang. Also—watch for my next update—it could be out at any moment.
Sincerely, Gary Silver
Managing Editor, Market Crux | 
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