Sunday, August 17, 2025

Low Float Biotech Profile (Nasdaq: MDCX) Takes Over Monday's Watchlist (5 Potential Catalysts)

*Disseminated on behalf of Medicus Pharma Ltd.


Low Float Biotech Profile (Nasdaq: MDCX) Takes Over Monday's Watchlist (5 Potential Catalysts)


August 17th

Greetings Readers,


In today’s fast-changing life sciences sector, a few companies stand out for advancing novel therapies that tackle serious unmet medical needs.


One such company, through its wholly owned subsidiary, is developing a dissolvable microneedle patch to deliver chemotherapy directly to tumors, aiming to change treatment for skin cancers like basal cell carcinoma.


Now in clinical trials in both the U.S. and United Arab Emirates, this method could challenge traditional cancer care by offering less invasive, more patient-friendly options than surgery or systemic treatment.


The company is also broadening its scope via strategic acquisitions, including a late-stage UK biotech focused on next-generation therapies for advanced prostate disease.


These moves reflect a wider ambition to influence multiple therapeutic areas, especially those needing safer, more effective solutions.


By drawing on a thesis-driven approach and deep industry ties, the company is working to speed the development and commercialization of groundbreaking treatments.


With the global biotech market rapidly expanding, such advances warrant attention for their potential to reshape standards of care in both human and veterinary medicine.


Plus, with a low float of fewer than 3Mn sharestwo analyst targets suggesting significant upside potential, and a definitive agreement in place working towards a momentous acquisition, there's little doubt why I've got my radar fixated on this new Nasdaq profile.



*Medicus Pharma Ltd. (Nasdaq: MDCX)*


Medicus Pharma Ltd. is a biotech/life sciences company focused on accelerating the clinical development programs of novel and disruptive therapeutics assets. The company is actively engaged in multiple countries, spread over three continents.


And based on several potential catalysts, (Nasdaq: MDCX) has pushed its way to the top of my watchlist. Take a look:


No. 1 - A Low Float Could Create The Environment For Heightened Volatility.


No. 2 - Medicus Signs MOU With Helix Nanotechnologies Inc. To Combine Key Company Platforms.


No. 3 - A Pair Of Analyst Targets Suggest Major Upside Potential (Triple-Digit!).


No. 4 - Medicus Seeks FDA Consent To Fast Track Clinical Development Program With Submission Of Type C Meeting Request.


No. 5 - A Definitive Agreement Moves Medicus Pharma A Step Closer To A Game-Changing Acquisition.


But more on those in a second...


Company Breakdown - Medicus Pharma Ltd. (Nasdaq: MDCX)


Medicus Pharma Ltd. specializes in rapidly moving forward the clinical development of cutting-edge therapeutic solutions within the biotech and life sciences sector.

About SkinJect - Medicus Pharma's (Nasdaq: MDCX) Wholly Owned Subsidiary


A novel non-invasive regimen to treat skin cancer; especially Basal Cell Carcinoma.


SkinJect Inc. is a development stage biotechnology life sciences company focused on commercializing novel treatment for non-melanoma skin cancer, especially basal cell carcinoma, using a patented dissolvable doxorubicincontaining microneedle arrays (D-MNA). D-MNA delivers the chemotherapeutic agent transdermally at the site of the lesion to eradicate tumor cells. The relevant US Patents were granted to University of Pittsburgh and Carnegie Mellon University in 2018.

SkinJect Inc. secured exclusive worldwide development and commercialization rights from University of Pittsburgh and Carnegie Mellon University in April 2016. The company attempts to provide an alternative to an invasive, painful, but effective treatment commonly called Mohs Surgery, by providing an efficacious, painless and easy to administer treatment in an office setting.


SkinJect Inc. has completed a Phase I study in March 2021 for participants with superficial and nodular Basal Cell Carcinoma (BCC). In January 2024 a Phase 2 IND clinical protocol was submitted to the FDA for a randomized, controlled, double-blind, multicenter study that is expected to randomize up to 60 patients. Patient recruitment began in August 2024 in 9 sites across the United States. A positively trending interim analysis in March 2025 showed more than 60% complete clinical response. In April 2025, IRB approved an increase in the number of patients from 60 to 90.


SkinJect Clinical Development Outlook

The SkinJect Value Proposition


1. Innovative Microneedle Patch Technology:


  • The company aims to provide an alternative to an invasive, painful, but effective treatment commonly called Mohs Surgery, by providing an efficacious, painless and easy to administer treatment in an office setting.
  • Patented technology for non-invasively treating skin cancer using cellulose-based microneedles to deliver cancer drugs directly to the tumor site
  • Exclusive worldwide development and commercialization rights from University of Pittsburgh and Carnegie Mellon University in April 2016.


2. Market Potential:


  • BCC is the most common and fastest-growing cancer globally.
  • >US$15Bn market for skin cancer treatments in North America by 2030. (1)
  • Potential for further market expansion and penetration by SkinJect’s novel treatment approach.


3. Positive Clinical Trial Results:


  • Phase 1 trial completed March 2021, demonstrating safety and tolerability.
  • In Q1 2024 a Phase 2 IND clinical protocol was submitted to the FDA for a randomized, controlled, double-blind, multicenter study.
  • In Q3 2024 Phase 2 enrollment began.
  • In Q1 2025 conducted interim analysis after 50% patient recruitment.
  • In Q2 2025, IRB approved to increase number of patients from 60 to 90.


4. Seasoned Leadership and Board:


  • Management team with public company experience.
  • Board includes industry veterans and experts in oncology and drug development.


Grab Key Sources: MDCX Presentation. MDCX Website.

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And as I mentioned previously, (Nasdaq: MDCX) has several potential catalysts that could generate breakout buzz. Check them out:


No. 1 MDCX Potential Catalyst - A Low Float Could Create The Environment For Heightened Volatility.


According to info from the Finviz websiteMDCX has a fairly low float.


The website reports this profile to have roughly 2.74Mn shares in its float.


Why is that important? It's important on one crucial level. Volatility potential.


If positive company news appears in the midway part of 2025, could it provide a breakout spark?

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No. 2 MDCX Potential Catalyst - Medicus Signs MOU With Helix Nanotechnologies Inc. To Combine Key Company Platforms.


Medicus Pharma Ltd. Announces a Memorandum of Understanding (MOU) with Helix Nanotechnologies Inc. to Develop Thermostable Infectious Disease Vac-cines


The MOU intends to combine proprietary mRNA vac-cine platform of HelixNano with proprietary Microneedle array (MNA) delivery platform of Medicus.


Philadelphia, Pennsylvania--(Newsfile Corp. - August 4, 2025) - Medicus Pharma Ltd. (NASDAQ: MDCX) ("Medicus") and Helix Nanotechnologies Inc. ("HelixNano"), a Boston-based biotech company focused on developing an advanced mRNA platform to create vac-cines and therapies to augment the immune system's power to fight disease, announced today that they have entered into a non-binding memorandum of understanding (the "MoU") in respect of their shared mutual interest in the development of thermostable infectious diseases vac-cines by combining HelixNano's proprietary mRNA vac-cine platform with Medicus' proprietary MNA delivery platform.


Subject to the certain conditions noted in the MoU, Medicus and HelixNano are currently engaged in good faith negotiations with the aim of forming a joint venture (the "Joint Venture") for the co-development and commercialization of thermostable mRNA-based vac-cines utilizing their respective proprietary technologies.


In parallel with such ongoing negotiations, Medicus and HelixNano have formalized their mutual intent to collaborate on the research, development and production of a batch of clinical-grade mRNA vac-cine-loaded MNAs (the "Project"), which are intended for use in a Phase 1 clinical bridging study to compare the safety and preliminary efficacy of intramuscular injection vs. intradermal MNA delivery of HelixNano's vac-cine candidate HN-0001, through the proposed Joint Venture.


"The potential of combining HelixNano's potent mRNA vaccine platform with our uniquely formulated dissolvable microneedle array (MNA) technology, is designed to unlock next generation vaccination paradigm," stated Dr. Raza Bokhari, Executive Chairman & CEO, "aiming to develop needle-free, thermostable vaccines that could eliminate cold-chain logistics, reduce distribution costs, improve patient access and offer global scale, which could potentially position us at the forefront of ground-breaking opportunities to prevent, rather than treat, infectious diseases. The Company is exploring numerous possibilities offered by microneedle arrays."


...


Read the full article here.

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No. 3 MDCX Potential Catalyst - A Pair Of Analyst Targets Suggest Major Upside Potential (Triple-Digit!).


Check out what MarketBeat is reporting:

As of Friday's close, MDCX had two different analyst targets pointing to a significant amount of upside potential.


Jason Kolbert of D. Boral Capital has given MDCX a $27 target representing a potential upside over 1,200% from last week's close.


Additionally, Jason McCarthy of Maxim Group has provided a $20 target suggesting 850+% potential upside from last week's close.


Could (Nasdaq: MDCX) be undervalued from current chart levels?

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No. 4 MDCX Potential Catalyst - Medicus Seeks FDA Consent To Fast Track Clinical Development Program With Submission Of Type C Meeting Request.


Medicus Pharma Ltd. Announces Submission of Type C Meeting Request to the Food and Drug Administration (FDA)


The Company's aim is to seek FDA consent to fast track the Clinical Development Program to treat Basal Cell Carcinoma (BCC) of the skin using Dissolvable Doxorubicin-containing Microneedle Arrays (D-MNA)


Philadelphia, Pennsylvania--(Newsfile Corp. - July 8, 2025) - Medicus Pharma Ltd. (NASDAQ: MDCX) ("Medicus" or the "Company") is pleased to announce submission of a comprehensive package to the United States Food and Drug Administration (the "FDA") seeking a Type C meeting with the FDA during the week of October 6th, 2025.


The purpose of the Type C meeting is to formally discuss the D-MNA product development and gain further alignment on the clinical pathway. The Company's aim is to gain the FDA's consent to fast-track the clinical development program and seek feedback on future clinical plans for the D-MNA development program. ...


...


Read the full article here.

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No. 5 MDCX Potential Catalyst - A Definitive Agreement Moves Medicus Pharma A Step Closer To A Game-Changing Acquisition.


Medicus Pharma Ltd Announces a Definitive Agreement to Acquire Antev Ltd. UK


Antev Shareholders to Receive Aggregate ~17% Equity Stake in Medicus plus US$65Mn in Contingent Payments


Philadelphia, Pennsylvania--(Newsfile Corp. - June 30, 2025) - Medicus Pharma Ltd. (NASDAQ: MDCX) ("Medicus") and Antev Ltd. ("Antev"), a UK-based clinical-stage drug development company, announced today that they have entered into a definitive agreement dated June 29, 2025 (the "Definitive Agreement") pursuant to which Medicus has agreed to acquire all of the issued and outstanding shares of Antev (the "Antev Shares") on a share exchange basis (the "Transaction").


Subject to the closing conditions noted in the Definitive Agreement, Medicus will acquire all issued and outstanding Antev Shares, on a fully diluted basis, in exchange for 2,666,600 (or approximately 17% in aggregate) of the issued and outstanding Medicus common shares (the "Consideration Shares").


...


The Transaction is expected to close before the end of August 2025, subject to the fulfillment of certain closing conditions, including obtaining Antev shareholder approval and other applicable corporate, regulatory and third-party approvals. No assurances can be given that the parties will successfully close the Transaction on the terms or timeframe currently contemplated or at all.


Antev is a clinical stage biotech company, developing Teverelix, a next generation GnRH antagonist, as first in market product for cardiovascular high-risk prostate cancer patients and patients with first acute urinary retention (AURr) episodes due to enlarged prostate.


Antev Acute Urinary Retention (AUR) Indication:


Teverelix is aiming to be the first-in-class indication product for preventing recurrence of acute urinary retention (AURr) in males 45 years or older, who suffer from prostate enlargement. Antev has a US Food and Drug Administration (FDA) approved phase 2b study designed to randomize 390 men after a successful trial without catheterization (TWOC). 85% of nearly one million (1M) annual AUR episodes in the US occur in Men 60+ who suffer from enlarged prostate that manifests with age and frequently is followed by a recurrent episode within 6 months for approximately 30% of men, presenting a potential market opportunity of more than US $2Bn annually.


Antev planned Phase 2b Study Design in Acute Urinary Retention:


Randomized controlled double blinded study in 390 men after a successful TWOC in 60-70 sites in United States (US) and European Union (EU). The participants shall receive either single intramuscular (IM) or subcutaneous (SC) injection (90mg or 120mg) or placebo in addition to standard therapy. Primary endpoint is a composite of AURr, need for surgery or poor urinary flow metrics in the first 28 weeks plus 24 weeks follow up.


Antev High Cardiovascular (CV) Risk Advanced Prostate Cancer (APC) indication:


Teverelix is aiming to be the best-in-class indication product for hormone therapy for advanced prostate cancer (APC) patients with increased CV risk. Antev has a US Food and Drug Administration (FDA) approved phase 2b open label study designed to recruit 40 men with advanced prostate cancer. Antev is targeting a niche in patients with increased CV risk, aiming to provide an androgen deprivation therapy (ADT) option with potentially lower cardiac toxicity than conventional GnRH agonists. If approved, Teverelix could become the first hormone therapy labeled specifically for treating prostate cancer in patients with a history of cardiovascular disease. 300,000 to 500,000 men in the US are living with advanced stage prostate cancer presenting a potential market opportunity of more than US $4Bn annually.


Antev planned Phase 2b Study Design in Advanced Prostate Cancer


Open label study in 40 men with advanced prostate cancer suitable for ADT. The participants shall receive a loading dose of 180mg IM plus x2 180mg SC (total 540mg), followed by x2 180mg (360mg) SC day 29 and every 6 weeks. The total duration of the treatment is 22 weeks. Primary endpoint is to confirm castration rate by day 29, sustaining to day 155, probability greater than 90%.


...


Read the full article here.

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(Nasdaq: MDCX) Recap - These 5 Potential Breakout Catalysts Lead The Way


No. 1 - A Low Float Could Create The Environment For Heightened Volatility.


No. 2 - Medicus Signs MOU With Helix Nanotechnologies Inc. To Combine Key Company Platforms.


No. 3 - A Pair Of Analyst Targets Suggest Major Upside Potential (Triple-Digit!).


No. 4 - Medicus Seeks FDA Consent To Fast Track Clinical Development Program With Submission Of Type C Meeting Request.


No. 5 - A Definitive Agreement Moves Medicus Pharma A Step Closer To A Game-Changing Acquisition.

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Coverage is officially initiated on Medicus Pharma Ltd. (Nasdaq: MDCX).


Be on the lookout for updates coming shortly.


Sincerely,

Kai Parker

StockWireNews


(Always Remember The St-ock Prices Could Be Significantly Lower Now From The Dates I Provided.)


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